Thyroid Disorders and Fatigue: Unveiling Hidden Causes


Thyroid disorders can significantly affect a woman’s energy levels, leading to chronic fatigue and other debilitating symptoms.

While high TSH levels are commonly associated with fatigue in hypothyroidism, there are often other underlying causes that are overlooked.

This blog post aims to shed light on some of these causes, by providing insights into how to address them through proper supplementation.

By understanding the role of various nutrients, such as iron, B12, folate, and ferritin, we can uncover potential solutions for combating fatigue and improving overall well-being.

1. The Impact of Anaemia on Thyroid Health

Anemia, characterized by insufficient iron levels, can significantly contribute to fatigue and low energy levels. Beyond iron deficiency, we should also consider B12 deficiency and folate deficiency, known as pernicious anemia.

By paying close attention to their iron, B12 and folate levels, women with Hashimoto’s and Graves’ disease can start to address potential causes of fatigue.

2. The Role of B12 Deficiency and Neurological Symptoms:

Low levels of vitamin B12, folate, and iron are found in women with Hashimoto’s and Graves’ disease and can manifest in neurological symptoms, including anxiety, depression, and generalized anxiety disorder.

Proper testing and supplementation, when necessary, are crucial for addressing B12 deficiency, folate and iron deficiencies, supporting not only improved health but an increase in energy.

3. Factors Affecting Nutrient Absorption

In addition to these deficiencies, poor nutrient absorption can also contribute to fatigue in thyroid disorders.

Certain factors hinder the absorption of essential nutrients like iron and B12. For example, zinc and calcium supplements, when taken too close to iron or B12 supplements, can interfere with absorption.

Likewise, substances like black tea, coffee, red wine, spinach, chocolate, and wheat bran can limit iron absorption.

It is worth noting that even though spinach is high in iron, its oxalate levels can hinder absorption. Adequate levels of vitamins A, B, C, and zinc, along with optimal stomach acid production, are crucial for efficient nutrient absorption.

4. Gene Mutations and Ferritin Levels

Gene mutations can affect the absorption of nutrients, such as B12 and folate. Specifically, the MTHFR gene mutation can lead to difficulties in absorbing folate and B12.

Iron is also an important component of thyroid peroxidase, an enzyme essential for thyroid hormone biosynthesis.

Ferritin and or Iron deficiency is common and is associated with fatigue, hair loss, insomnia, mood swings, and unusual food cravings.

Identifying the source of iron and or ferritin deficiency is important for treating it, especially for women who are exercising, menstruating and those with gastrointestinal issues as identifying the root cause is essential for effective treatment.

5. The Importance of Testing and Supplementation

To address these underlying issues, comprehensive testing is crucial in identifying specific nutrient deficiencies, including DNA testing for gene mutations and absorption issues.

Supplementation can be beneficial; however, it is essential to test nutrient levels before starting any supplementation regimen, ensuring the correct dosage and type of supplements used. And recheck every 3-4 months and adjust if required.


Fatigue is a common struggle for women with thyroid disorders, and it can stem from various factors beyond high TSH levels. Anaemia, nutrient absorption issues, gene mutations, and ferritin deficiencies can significantly affect energy levels and overall well-being.

By conducting thorough testing and implementing targeted supplementation, women with thyroid disorders can address these underlying issues and regain their energy and vitality.

Take charge of your thyroid health and live a life filled with energy and vitality!

Book your naturopathic appointment with Louise here